International Journal of Education and Research in Health Sciences
(Official Publication of Sai Amrut Educational and Medical Research Foundation, Aurangabad)
 

Vol.1, Issue 2 (2018)



Persistent Müllerian Duct Syndrome: Fertility Challenge

Hemraz Palawan, Sultan Al Thakafi, Serdar Coskun, Naif Al Hathal



Abstract

Persistent Müllerian duct syndrome (PMDS) is a rare, autosomal recessive disorder of sex development, of male pseudohermaphroditism, characterized by the persistence of Müllerian duct derivatives: uterus, fallopian tubes, and upper vagina. Mutations of the gene or the receptor of anti-Müllerian hormone (AMH) are responsible for clinical symptoms of PMDS, with subjects having a 46 XY karyotype and a male phenotype. We report the case of a 23-year-old male patient with bilateral undescended testes (UDT) and the surgical management as well as briefly the ethical principles behind the certain clinical decision. In conclusion, we suggest that such cases need a holistic approach with a multidisciplinary team as well as patient and health care professional education.


Keywords

Anti-Müllerian hormone, Autonomy, Beneficence, Hormones, Persistent Müllerian duct syndrome, Surgical management, Undescended testis.


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International Journal of Education and Research in Health Sciences






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