Evaluation of Efficacy of Subconjunctival Injection Bevacizumab (Avastin) in the Treatment of Neovascular Glaucoma
Kokila G Kamath, Kasturi S Chavan, Rajratna G Nithaal, Kailash Prasad, Vishal S Jadhav
Neovascular glaucoma (NVG) is a potentially devastating sequel of serious underlying ocular/systemic diseases. The ocular diseases responsible for neovascularization of iris (NVI)/ neovascularization of the angle (NVA) ultimately leading to NVG are almost always ischemic in nature. Under hypoxic conditions, diffuse angiogenic factors, including vascular endothelial growth factor (VEGF), have been detected in human retina and vitreous promoting new vessel growth. Three important common conditions responsible for NVG are diabetic retinopathy, central retinal vein occlusion (CRVO), and carotid artery obstructive diseases. No treatment has been found to be effective. We have studied these cases with subconjunctival injection Avastin with excellent results.
Avastin, Bevacizumab, Neovascular glaucoma, New vessels at the angle, New vessels on iris, Subconjunctival