Role of Tc-99m Pertechnetate Thyroid Scan to detect Thyroid Gland in Congenital Hypothyroidism: A Comparison with Ultrasound
Shwetal U Pawar, Anuja Anand, Bhairavi M Bhatt, Suruchi S Shetye, Mangala K Ghorpade
INTRODUCTION: The detection of functioning thyroid tissue is the key information to assess the hormone replacement in congenital hypothyroidism (CH). The purpose of the study was to assess the role of Tc-99m pertechnetate thyroid scintigraphy (TS) and ultrasound in detecting the eutopic and ectopic thyroid tissue. MATERIALS AND METHODS: A retrospective observational study was done in which 37 children (12 boys and 25 girls), who underwent TS and ultrasound of neck to look for the thyroid tissue. The TS and ultrasound were compared so as to diagnose athyreosis, thyroid hypoplasia, and ectopic thyroid. A Chi-square test was applied to find the difference between the two investigations with 5% confidence limit. RESULTS: Athyreosis (53%) was the most common reason for hypothyroidism and lingual (53.3%) was the most common location of ectopic thyroid tissue. The sensitivity of ultrasound and TS for detection of eutopic thyroid gland was found to be 100 and 84.62% respectively. However, the sensitivity of ultrasound and TS to detect ectopically located thyroid tissue was 29 and 100% respectively. The dual ectopic location of thyroid was also detected in 26.6% on TS. CONCLUSION: The TS performed better to detect the ectopic thyroid tissue, whereas ultrasound was better to detect the thyroid tissue in the normal location.
Athyreosis, Ectopic, Eutopic, Hypoplasia, Thyroid scintigraphy, Ultrasound